Version: 8.2.0Date: Wed Aug 27 2025
Gene Molecular Function: sequence-specific DNA binding
Sox9
(Rattus norvegicus)Gene
Name: SRY-box transcription factor 9
Synonyms: SRY-box containing gene 9, SRY box 9, LOC363699, SRY (sex determining region Y)-box 9, transcription factor SOX-9, LOC100361122, SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal), SRY
Source: RGD:620474
Biotype: protein coding gene
TP53
(Homo sapiens)Gene
Name: tumor protein p53
Synonyms: cellular tumor antigen p53, tumor supressor p53, BCC7, transformation-related protein 53, antigen NY-CO-13, p53 transformation suppressor, mutant tumor protein 53, P53, phosphoprotein p53, p53 antigen, TRP53, FLJ92943, mutant p53 protein, tumor protein 53, tumor suppressor TP53, tumor suppressor p53, LFS1, BMFS5, p53 tumor suppressor, truncated p53 protein
Source: HGNC:11998
Biotype: protein coding gene
Msx1
(Mus musculus)Gene
Name: msh homeobox 1
Synonyms: Hox-7, AA675338, msh, expressed sequence AI324650, homeo box-7 cluster, msh-like, Hox7, AI324650, expressed sequence AA675338, muscle-segment homeobox, Hox7.1
Source: MGI:97168
Biotype: protein coding gene
BRCA1
(Homo sapiens)Gene
Name: BRCA1 DNA repair associated
Synonyms: RNF53, early onset breast cancer 1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast cancer 1, BRCC1, BRCA1, DNA repair associated, breast and ovarian cancer susceptibility protein 1, BRCA1/BRCA2-containing complex, subunit 1, RING finger protein 53, breast cancer 1, early onset, Fanconi anemia, complementation group S, IRIS, breast cancer type 1 susceptibility protein, PNCA4, BRCAI, PSCP, BROVCA1, truncated BRCA1, protein phosphatase 1, regulatory subunit 53, breast cancer 1, PPP1R53, FANCS
Source: HGNC:1100
Biotype: protein coding gene
pax2a
(Danio rerio)Gene
Name: paired box 2a
Synonyms: no isthmus, pax2.1, pax-b, cb378, pax[zf-b], pax2a1, noi, Pax-2, paxb, Pax2.1
Source: ZFIN:ZDB-GENE-990415-8
Biotype: protein coding gene
Pax6
(Mus musculus)Gene
Name: paired box 6
Synonyms: 1500038E17Rik, AEY11, RIKEN cDNA 1500038E17 gene, Pax-6, Sey, gsf abnormal eyes 11, Dey, Dickie's small eye, Gsfaey11, small eye
Source: MGI:97490
Biotype: protein coding gene
Trp53
(Mus musculus)Gene
Name: transformation related protein 53
Synonyms: p44, p53
Source: MGI:98834
Biotype: protein coding gene
STAT5B
(Homo sapiens)Gene
Name: signal transducer and activator of transcription 5B
Synonyms: transcription factor STAT5B, STAT5, GHISID2
Source: HGNC:11367
Biotype: protein coding gene
ss
(Drosophila melanogaster)Gene
Name: spineless
Synonyms: SS, ssa, Ss, Spineless, CG6993, aristapedia, dAHR, AhR, AHR, spineless-aristapedia
Source: FB:FBgn0003513
Biotype: protein coding gene
sox9a
(Danio rerio)Gene
Name: SRY-box transcription factor 9a
Synonyms: jellyfish, wu:fj17b12, zgc:111921, jef
Source: ZFIN:ZDB-GENE-001103-1
Biotype: protein coding gene
APP
(Homo sapiens)Gene
Name: amyloid beta precursor protein
Synonyms: AAA, ABETA, PN-II, beta-amyloid peptide, beta-amyloid peptide(1-42), beta-amyloid peptide(1-40), preA4, cerebral vascular amyloid peptide, testicular tissue protein Li 2, peptidase nexin-II, alpha-sAPP, AD1, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease), protease nexin-II, CTFgamma, amyloid beta A4 protein, PN2, APPI, alzheimer disease amyloid A4 protein homolog, CVAP, ABPP
Source: HGNC:620
Biotype: protein coding gene
PAX6
(Homo sapiens)Gene
Name: paired box 6
Synonyms: paired box 6 PAX6A-ASdel6-AS7 isoform, paired box homeotic gene-6, AN1, AN2, paired box 6 PAX6B-ASdel6 isoform, AN, D11S812E, paired box 6 PAX6A-del6 isoform, paired box protein Pax-6, MGDA, Aniridia 1, Aniridia 2, aniridia type II protein, oculorhombin, paired box 6 PAX6-12a isoform, FVH1, MGC17209, paired box 6 PAX6D isoform, ASGD5, WAGR, paired box 6 PAX6A-ASdel6 isoform, alternative protein PAX6
Source: HGNC:8620
Biotype: protein coding gene
TNF
(Homo sapiens)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor ligand superfamily member 2, TNF-a, TNF-alpha, tumor necrotic factor alpha, TNLG1F, tumor necrosis factor-alpha, TNFSF2, TNF, monocyte-derived, TNFA, tumor necrosis factor alpha, TNF, macrophage-derived, tumor necrosis factor ligand 1F, IMD127, TNF superfamily, member 2, APC1 protein, cachectin
Source: HGNC:11892
Biotype: protein coding gene
MYC
(Homo sapiens)Gene
Name: MYC proto-oncogene, bHLH transcription factor
Synonyms: proto-oncogene c-Myc, avian myelocytomatosis viral oncogene homolog, c-Myc, MYCC, v-myc myelocytomatosis viral oncogene homolog, myc proto-oncogene protein, class E basic helix-loop-helix protein 39, transcription factor p64, MRTL, bHLHe39, cMyc, myc-related translation/localization regulatory factor, v-myc avian myelocytomatosis viral oncogene homolog
Source: HGNC:7553
Biotype: protein coding gene
SSN8
(Saccharomyces cerevisiae)Gene
Name: Suppressor of SNf1
Synonyms: UME3, RYE2, SRB11, CycC, CNC1, NUT9, YNL025C, GIG3
Source: SGD:S000004970
Biotype: protein coding gene
Sox7
(Mus musculus)Gene
Name: SRY (sex determining region Y)-box 7
Synonyms: Not Available
Source: MGI:98369
Biotype: protein coding gene
SNCA
(Homo sapiens)Gene
Name: synuclein alpha
Synonyms: non-A beta component of AD amyloid, PARK1, MGC110988, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein, alpha (non A4 component of amyloid precursor), NACP, truncated alpha synuclein, I+/--synuclein, alpha-synuclein, isoform NACP140, synuclein, alpha, alpha-synuclein, PARK4, synuclein alpha-140, non-A4 component of amyloid, PD1, non A-beta component of AD amyloid
Source: HGNC:11138
Biotype: protein coding gene
Tardbp
(Mus musculus)Gene
Name: TAR DNA binding protein
Synonyms: Tdp43, 1190002A23Rik, TDP-43, expressed sequence C85084, Tdp-43, RIKEN cDNA 1190002A23 gene, C85084
Source: MGI:2387629
Biotype: protein coding gene
Tnf
(Mus musculus)Gene
Name: tumor necrosis factor
Synonyms: DIF, tumor necrosis factor-alpha, Tnfa, TNF alpha, TNF-alpha, TNFalpha, tumor necrosis factor, alpha, Tnfsf1a, RATTNF
Source: MGI:104798
Biotype: protein coding gene
BCL2
(Homo sapiens)Gene
Name: BCL2 apoptosis regulator
Synonyms: Bcl-2, protein phosphatase 1, regulatory subunit 50, Bcl-2a, PPP1R50, B-cell CLL/lymphoma 2, b-cell leukemia/lymphoma 2, Bcl-2ß, apoptosis regulator Bcl-2, BCL2, apoptosis regulator
Source: HGNC:990
Biotype: protein coding gene
SIRT1
(Homo sapiens)Gene
Name: sirtuin 1
Synonyms: SIR2-like protein 1, NAD-dependent protein deacylase sirtuin-1, SIR2alpha, SIR2, sir2-like 1, sirtuin, SIR2L1, regulatory protein SIR2 homolog 1, NAD-dependent protein deacetylase sirtuin-1, hSIRT1, hSIR2, NAD-dependent deacetylase sirtuin-1, sirtuin type 1
Source: HGNC:14929
Biotype: protein coding gene
App
(Mus musculus)Gene
Name: amyloid beta precursor protein
Synonyms: Cvap, Abeta, cerebrovascular amyloid peptide, Alzheimer disease amyloid beta protein, protease nexin II, RIKEN cDNA E030013M08 gene, AL024401, expressed sequence AL024401, betaAPP, E030013M08Rik, Adap, appican
Source: MGI:88059
Biotype: protein coding gene
HSF1
(Saccharomyces cerevisiae)Gene
Name: Heat Shock transcription Factor
Synonyms: YGL073W, EXA3, MAS3
Source: SGD:S000003041
Biotype: protein coding gene
MTOR
(Homo sapiens)Gene
Name: mechanistic target of rapamycin kinase
Synonyms: tyrosine-protein kinase mTOR, mechanistic target of rapamycin, rapamycin and FKBP12 target 1, rapamycin target protein 1, rapamycin associated protein FRAP2, mammalian target of rapamycin, FRAP1, RAFT1, FRAP2, FKBP12-rapamycin complex-associated protein 1, mechanistic target of rapamycin (serine/threonine kinase), FLJ44809, FRAP, SKS, RAPT1, serine/threonine-protein kinase mTOR, FKBP-rapamycin associated protein, FK506-binding protein 12-rapamycin complex-associated protein 1, FK506 binding protein 12-rapamycin associated protein 1, FK506 binding protein 12-rapamycin associated protein 2
Source: HGNC:3942
Biotype: protein coding gene
Evx1
(Mus musculus)Gene
Name: even-skipped homeobox 1
Synonyms: Evx-1, even skipped homeotic gene 1 homolog
Source: MGI:95461
Biotype: protein coding gene
pax6a
(Danio rerio)Gene
Name: paired box 6a
Synonyms: paxzfa, fc20e07, Pax6.1, pax-a, wu:fc20e07, pax[zf-a], zfpax-6b, zfpax-6a, etID309716.25, cb280, pax6
Source: ZFIN:ZDB-GENE-990415-200
Biotype: protein coding gene
Stat3
(Mus musculus)Gene
Name: signal transducer and activator of transcription 3
Synonyms: RIKEN cDNA 1110034C02 gene, expressed sequence AW109958, 1110034C02Rik, Aprf, AW109958
Source: MGI:103038
Biotype: protein coding gene
Pou5f1
(Mus musculus)Gene
Name: POU domain, class 5, transcription factor 1
Synonyms: Oct-4, Oct-3, Otf-4, Otf-3, octamer binding transcription factor 4, octamer binding transcription factor 3, Oct3/4, Oct4, Otf4, Otf3, Oct-3/4, Otf3-rs7, Otf3g, octamer binding transcription factor 3 related sequence 7
Source: MGI:101893
Biotype: protein coding gene
daf-16
(Caenorhabditis elegans)Gene
Name: abnormal DAuer Formation 16
Synonyms: daf-17, R13H8.1, CELE_R13H8.1
Source: WB:WBGene00000912
Biotype: protein coding gene
TP53BP1
(Homo sapiens)Gene
Name: tumor protein p53 binding protein 1
Synonyms: p53-binding protein 1, tumor protein p53-binding protein, 1, FLJ41424, TDRD30, p53BP1, MGC138366, 53BP1, p202, tumor protein 53-binding protein, 1, TP53-binding protein 1, TP53, tumor suppressor p53-binding protein 1
Source: HGNC:11999
Biotype: protein coding gene
Emx1
(Mus musculus)Gene
Name: empty spiracles homeobox 1
Synonyms: RGD1564002
Source: MGI:95387
Biotype: protein coding gene
KAT2B
(Homo sapiens)Gene
Name: lysine acetyltransferase 2B
Synonyms: P, spermidine acetyltransferase KAT2B, P/CAF, p300/CBP-associated factor, K(lysine) acetyltransferase 2B, histone acetyltransferase KAT2B, histone acetylase PCAF, CAF, histone acetyltransferase PCAF, PCAF, CREBBP-associated factor
Source: HGNC:8638
Biotype: protein coding gene
ACE2
(Saccharomyces cerevisiae)Gene
Name: Activator of CUP1 Expression
Synonyms: YLR131C
Source: SGD:S000004121
Biotype: protein coding gene
GAL4
(Saccharomyces cerevisiae)Gene
Name: GALactose metabolism
Synonyms: YPL248C, GAL81
Source: SGD:S000006169
Biotype: protein coding gene
Rag2
(Mus musculus)Gene
Name: recombination activating gene 2
Synonyms: Rag-2
Source: MGI:97849
Biotype: protein coding gene
Foxp2
(Mus musculus)Gene
Name: forkhead box P2
Synonyms: 2810043D05Rik, RGD1559697, RIKEN cDNA 2810043D05 gene, AI449000, expressed sequence AI449000, D0Kist7, DNA segment, KIST 7
Source: MGI:2148705
Biotype: protein coding gene
Mef2c
(Mus musculus)Gene
Name: myocyte enhancer factor 2C
Synonyms: RIKEN cDNA 5430401D19 gene, RIKEN cDNA 9930028G15 gene, 5430401D19Rik, AV011172, expressed sequence AV011172, RGD1563119, 9930028G15Rik
Source: MGI:99458
Biotype: protein coding gene
Foxp3
(Mus musculus)Gene
Name: forkhead box P3
Synonyms: RGD1562112, sf, scurfy, scurfin, JM2
Source: MGI:1891436
Biotype: protein coding gene
Pparg
(Mus musculus)Gene
Name: peroxisome proliferator activated receptor gamma
Synonyms: PPARgamma2, Nr1c3, Ppar-gamma2, PPARgamma, PPAR-gamma
Source: MGI:97747
Biotype: protein coding gene
Sry
(Mus musculus)Gene
Name: sex determining region of Chr Y
Synonyms: testis determining factor, SRYGENE, Tdf, Tdy, testis determining-Y, Sry3B
Source: MGI:98660
Biotype: protein coding gene
MCM1
(Saccharomyces cerevisiae)Gene
Name: MiniChromosome Maintenance
Synonyms: FUN80, YMR043W
Source: SGD:S000004646
Biotype: protein coding gene
Brca1
(Mus musculus)Gene
Name: breast cancer 1, early onset
Synonyms: BRCA-1
Source: MGI:104537
Biotype: protein coding gene
fkh-2
(Caenorhabditis elegans)Gene
Name: ForKHead transcription factor family 2
Synonyms: T14G12.4, CELE_T14G12.4
Source: WB:WBGene00001434
Biotype: protein coding gene
Ezh2
(Mus musculus)Gene
Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
Synonyms: enhancer of zeste homolog (Drosophila), Enx-1, Enx1h, KMT6
Source: MGI:107940
Biotype: protein coding gene
NLRP3
(Homo sapiens)Gene
Name: NLR family pyrin domain containing 3
Synonyms: caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, cryopyrin, NACHT, LRR and PYD domains - containing protein 3, deafness, autosomal dominant 34, CIAS1, NACHT, LRR and PYD domains-containing protein 3, cold autoinflammatory syndrome 1, FCAS, cryopyrin, NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3, AII/AVP receptor-like, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3, FCAS1, AGTAVPRL, DFNA34, AII, CLR1.1, MWS, PYPAF1, AII/AVP, NACHT, LRR and PYD containing protein 3, NLR family, pyrin domain containing 3, FLJ95925, NALP3, C1orf7, angiotensin/vasopressin receptor AII/AVP-like, FCU, AVP, KEFH
Source: HGNC:16400
Biotype: protein coding gene
mitfa
(Danio rerio)Gene
Name: melanocyte inducing transcription factor a
Synonyms: nac, z3A.1, nacre, Mitf2, Mitf-related gene
Source: ZFIN:ZDB-GENE-990910-11
Biotype: protein coding gene
Eomes
(Mus musculus)Gene
Name: eomesodermin
Synonyms: T-box brain gene 2, C77258, Tbr2, expressed sequence C77258
Source: MGI:1201683
Biotype: protein coding gene
Ahr
(Mus musculus)Gene
Name: aryl-hydrocarbon receptor
Synonyms: Ahh, bHLHe76, dioxin receptor, Ahre, In, Ah, aryl hydrocarbon hydroxylase, inflammatory reactivity, aromatic hydrocarbon responsiveness
Source: MGI:105043
Biotype: protein coding gene
ALX3
(Homo sapiens)Gene
Name: ALX homeobox 3
Synonyms: homeobox protein aristaless-like 3, FND1, MGC138212, aristaless-like homeobox 3, frontonasal dysplasia, proline-rich transcription factor ALX3, FND, MGC141988
Source: HGNC:449
Biotype: protein coding gene
p53
(Drosophila melanogaster)Gene
Name: p53
Synonyms: CG33336, CG10873, dp53, DMP53, Dp53, P53, prac, dmp53, D-p53, Dmp53, DmP53, Dm-P53, dmP53, protein 53, CG31325, Drosophila p53, p53-like regulator of apoptosis and cell cycle
Source: FB:FBgn0039044
Biotype: protein coding gene